Q14974 - Importin subunit beta-1

Protein
Importin subunit beta-1
Gene
KPNB1
Reference
UniProtKB reviewed (Swiss-Prot)
Amino acids
876
Disorder5.80%
LIP3.20%
Domain100.00%

Disorder
F
   
MobiDB-lite
P
   
AlphaFold-disorder (RSA)
P
Linear interacting peptide
F
......................................DisorderObservedDisorderObservedDisorderObservedStructureObservedStructureStructureLipLipLipLip1100200300400500600700800
F
Consensus
C
Curated
D
Derived
H
Homology
P
Predicted

AlphaFold Q14974

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Annotation source Priority consensus
Coverage 5.8%
Disorder residues
Intrisically disordered residues
Curated | hasDbXref
Coverage 93.3%
Observed residues
Experimentally observed residues in the PDB structure (X-ray, NMR, Cryo-EM)
Derived | ECO:0007297
Coverage 0.9%
Structure
Structured residues
Predicted
M
E
L
I
T
I
L
E
K
10T
V
S
P
D
R
L
E
L
E
20A
A
Q
K
F
L
E
R
A
A
30V
E
N
L
P
T
F
L
V
E
40L
S
R
V
L
A
N
P
G
N
50S
Q
V
A
R
V
A
A
G
L
60Q
I
K
N
S
L
T
S
K
D
70P
D
I
K
A
Q
Y
Q
Q
R
80W
L
A
I
D
A
N
A
R
R
90E
V
K
N
Y
V
L
Q
T
L
100G
T
E
T
Y
R
P
S
S
A
110S
Q
C
V
A
G
I
A
C
A
120E
I
P
V
N
Q
W
P
E
L
130I
P
Q
L
V
A
N
V
T
N
140P
N
S
T
E
H
M
K
E
S
150T
L
E
A
I
G
Y
I
C
Q
160D
I
D
P
E
Q
L
Q
D
K
170S
N
E
I
L
T
A
I
I
Q
180G
M
R
K
E
E
P
S
N
N
190V
K
L
A
A
T
N
A
L
L
200N
S
L
E
F
T
K
A
N
F
210D
K
E
S
E
R
H
F
I
M
220Q
V
V
C
E
A
T
Q
C
P
230D
T
R
V
R
V
A
A
L
Q
240N
L
V
K
I
M
S
L
Y
Y
250Q
Y
M
E
T
Y
M
G
P
A
260L
F
A
I
T
I
E
A
M
K
270S
D
I
D
E
V
A
L
Q
G
280I
E
F
W
S
N
V
C
D
E
290E
M
D
L
A
I
E
A
S
E
300A
A
E
Q
G
R
P
P
E
H
310T
S
K
F
Y
A
K
G
A
L
320Q
Y
L
V
P
I
L
T
Q
T
330L
T
K
Q
D
E
N
D
D
D
340D
D
W
N
P
C
K
A
A
G
350V
C
L
M
L
L
A
T
C
C
360E
D
D
I
V
P
H
V
L
P
370F
I
K
E
H
I
K
N
P
D
380W
R
Y
R
D
A
A
V
M
A
390F
G
C
I
L
E
G
P
E
P
400S
Q
L
K
P
L
V
I
Q
A
410M
P
T
L
I
E
L
M
K
D
420P
S
V
V
V
R
D
T
A
A
430W
T
V
G
R
I
C
E
L
L
440P
E
A
A
I
N
D
V
Y
L
450A
P
L
L
Q
C
L
I
E
G
460L
S
A
E
P
R
V
A
S
N
470V
C
W
A
F
S
S
L
A
E
480A
A
Y
E
A
A
D
V
A
D
490D
Q
E
E
P
A
T
Y
C
L
500S
S
S
F
E
L
I
V
Q
K
510L
L
E
T
T
D
R
P
D
G
520H
Q
N
N
L
R
S
S
A
Y
530E
S
L
M
E
I
V
K
N
S
540A
K
D
C
Y
P
A
V
Q
K
550T
T
L
V
I
M
E
R
L
Q
560Q
V
L
Q
M
E
S
H
I
Q
570S
T
S
D
R
I
Q
F
N
D
580L
Q
S
L
L
C
A
T
L
Q
590N
V
L
R
K
V
Q
H
Q
D
600A
L
Q
I
S
D
V
V
M
A
610S
L
L
R
M
F
Q
S
T
A
620G
S
G
G
V
Q
E
D
A
L
630M
A
V
S
T
L
V
E
V
L
640G
G
E
F
L
K
Y
M
E
A
650F
K
P
F
L
G
I
G
L
K
660N
Y
A
E
Y
Q
V
C
L
A
670A
V
G
L
V
G
D
L
C
R
680A
L
Q
S
N
I
I
P
F
C
690D
E
V
M
Q
L
L
L
E
N
700L
G
N
E
N
V
H
R
S
V
710K
P
Q
I
L
S
V
F
G
D
720I
A
L
A
I
G
G
E
F
K
730K
Y
L
E
V
V
L
N
T
L
740Q
Q
A
S
Q
A
Q
V
D
K
750S
D
Y
D
M
V
D
Y
L
N
760E
L
R
E
S
C
L
E
A
Y
770T
G
I
V
Q
G
L
K
G
D
780Q
E
N
V
H
P
D
V
M
L
790V
Q
P
R
V
E
F
I
L
S
800F
I
D
H
I
A
G
D
E
D
810H
T
D
G
V
V
A
C
A
A
820G
L
I
G
D
L
C
T
A
F
830G
K
D
V
L
K
L
V
E
A
840R
P
M
I
H
E
L
L
T
E
850G
R
R
S
K
T
N
K
A
K
860T
L
A
T
W
A
T
K
E
L
870R
K
L
K
N
Q
A
A
A
A
A

Interactors

Protein
  Accession GeneNamePDBs Contacts
Protein--216
O95149SNUPNSnurportin-1639
Q14974KPNB1Importin subunit beta-1422
Q02630NUP116Nucleoporin NUP116/NSP11646
P14907NSP1Nucleoporin NSP137
P52292KPNA2Importin subunit alpha-1332
P62826RANGTP-binding nuclear protein Ran222
P07305H1-0Histone H1.022
P12272PTHLHParathyroid hormone-related protein16
O95863SNAI1Zinc finger protein SNAI1121
DNA
  Accession GeneNamePDBs Contacts
Other
  Accession GeneNamePDBs Contacts
other--21

Subcellular locations


Cross References

AlphaFold-disorder (RSA)